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Induction of Immunological Tolerance to Adenoviral Vectors by Using a Novel Dendritic Cell-Based Strategy
The success of helper-dependent adenoviral (HD-Ad) vector-mediated lung gene therapy is hampered by the host immune response, which limits pulmonary transgene expression following multiple rounds of vector readminstration. Here, we show that HD-Ad-mediated pulmonary gene expression is sustained even...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302513/ https://ncbi.nlm.nih.gov/pubmed/22258241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06172-11 |
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