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Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

Most of an intravenous dose of species C adenovirus serotype 5 (Ad5) is destroyed by liver Kupffer cells. In contrast, another species C virus, Ad6, evades these cells to mediate more efficient liver gene delivery. Given that this difference in Kupffer cell interaction is mediated by the hypervariab...

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Detalhes bibliográficos
Main Authors: Khare, Reeti, Reddy, Vijay S., Nemerow, Glen R., Barry, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302413/
https://ncbi.nlm.nih.gov/pubmed/22156515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05760-11
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