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Selection and Accumulation of an HIV-1 Escape Mutant by Three Types of HIV-1-Specific Cytotoxic T Lymphocytes Recognizing Wild-Type and/or Escape Mutant Epitopes

It is known that cytotoxic T lymphocytes (CTLs) recognizing HIV-1 escape mutants are elicited in HIV-1-infected individuals, but their role in the control of HIV-1 replication remains unclear. We investigated the antiviral ability of CTLs recognizing the HLA-A*24:02-restricted Gag28 -36 (KYKLKHIVW)...

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Bibliografiska uppgifter
Huvudupphovsmän: Akahoshi, Tomohiro, Chikata, Takayuki, Tamura, Yoshiko, Gatanaga, Hiroyuki, Oka, Shinichi, Takiguchi, Masafumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302409/
https://ncbi.nlm.nih.gov/pubmed/22156528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06470-11
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