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Molecular differences between a mutase and a phosphatase: Investigations of the activation step in Bacillus cereus phosphopentomutase

Prokaryotic phosphopentomutases (PPMs) are di-Mn(2+) enzymes that catalyze the interconversion of α-d-ribose 5-phosphate and α-d-ribose 1-phosphate at an active site located between two independently-folded domains. These prokaryotic PPMs belong to the alkaline phosphatase superfamily, but previous...

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Detalhes bibliográficos
Main Authors: Iverson, T. M., Panosian, Timothy D., Birmingham, William R., Nannemann, David P., Bachmann, Brian O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302354/
https://ncbi.nlm.nih.gov/pubmed/22329805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201761h
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