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Genome-Wide Networks of Amino Acid Covariances Are Common among Viruses

Coordinated variation among positions in amino acid sequence alignments can reveal genetic dependencies at noncontiguous positions, but methods to assess these interactions are incompletely developed. Previously, we found genome-wide networks of covarying residue positions in the hepatitis C virus g...

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Detalhes bibliográficos
Main Authors: Donlin, Maureen J., Szeto, Brandon, Gohara, David W., Aurora, Rajeev, Tavis, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302335/
https://ncbi.nlm.nih.gov/pubmed/22238298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06857-11
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