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Genome-wide hepatitis C virus amino acid covariance networks can predict response to antiviral therapy in humans
Hepatitis C virus (HCV) is a common RNA virus that causes hepatitis and liver cancer. Infection is treated with IFN-α and ribavirin, but this expensive and physically demanding therapy fails in half of patients. The genomic sequences of independent HCV isolates differ by approximately 10%, but the e...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613460/ https://ncbi.nlm.nih.gov/pubmed/19104147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37085 |
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