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Hepatitis C Virus Diversity and Evolution in the Full Open-Reading Frame during Antiviral Therapy

BACKGROUND: Pegylated interferon plus ribavirin therapy for hepatitis C virus (HCV) fails in approximately half of genotype 1 patients. Treatment failure occurs either by nonresponse (minimal declines in viral titer) or relapse (robust initial responses followed by rebounds of viral titers during or...

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Detalhes bibliográficos
Main Authors: Cannon, Nathan A., Donlin, Maureen J., Fan, Xiaofeng, Aurora, Rajeev, Tavis, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373758/
https://ncbi.nlm.nih.gov/pubmed/18463735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002123
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