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Beyond Anchoring: the Expanding Role of the Hendra Virus Fusion Protein Transmembrane Domain in Protein Folding, Stability, and Function

While work with viral fusion proteins has demonstrated that the transmembrane domain (TMD) can affect protein folding, stability, and membrane fusion promotion, the mechanism(s) remains poorly understood. TMDs could play a role in fusion promotion through direct TMD-TMD interactions, and we have rec...

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Autors principals: Smith, Everett Clinton, Culler, Megan R., Hellman, Lance M., Fried, Michael G., Creamer, Trevor P., Dutch, Rebecca Ellis
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302297/
https://ncbi.nlm.nih.gov/pubmed/22238302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05762-11
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