Naturally Occurring Antibodies That Recognize Linear Epitopes in the Amino Terminus of the Hepatitis C Virus E2 Protein Confer Noninterfering, Additive Neutralization

Chronic hepatitis C virus (HCV) infection can persist even in the presence of a broadly neutralizing antibody response. Various mechanisms that underpin viral persistence have been proposed, and one of the most recently proposed mechanisms is the presence of interfering antibodies that negate neutra...

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Bibliographische Detailangaben
Hauptverfasser: Tarr, Alexander W., Urbanowicz, Richard A., Jayaraj, Dhanya, Brown, Richard J. P., McKeating, Jane A., Irving, William L., Ball, Jonathan K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302288/
https://ncbi.nlm.nih.gov/pubmed/22171278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06492-11
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