Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages

Genome sequences of transmitted/founder (T/F) HIV-1 have been inferred by analyzing single genome amplicons of acute infection plasma viral RNA in the context of a mathematical model of random virus evolution; however, few of these T/F sequences have been molecularly cloned and biologically characte...

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Autors principals: Ochsenbauer, Christina, Edmonds, Tara G., Ding, Haitao, Keele, Brandon F., Decker, Julie, Salazar, Maria G., Salazar-Gonzalez, Jesus F., Shattock, Robin, Haynes, Barton F., Shaw, George M., Hahn, Beatrice H., Kappes, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302286/
https://ncbi.nlm.nih.gov/pubmed/22190722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06157-11
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