Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

Identification of full-length transmitted HIV-1 genomes could be instrumental in HIV-1 pathogenesis, microbicide, and vaccine research by enabling the direct analysis of those viruses actually responsible for productive clinical infection. We show in 12 acutely infected subjects (9 clade B and 3 cla...

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Hauptverfasser: Salazar-Gonzalez, Jesus F., Salazar, Maria G., Keele, Brandon F., Learn, Gerald H., Giorgi, Elena E., Li, Hui, Decker, Julie M., Wang, Shuyi, Baalwa, Joshua, Kraus, Matthias H., Parrish, Nicholas F., Shaw, Katharina S., Guffey, M. Brad, Bar, Katharine J., Davis, Katie L., Ochsenbauer-Jambor, Christina, Kappes, John C., Saag, Michael S., Cohen, Myron S., Mulenga, Joseph, Derdeyn, Cynthia A., Allen, Susan, Hunter, Eric, Markowitz, Martin, Hraber, Peter, Perelson, Alan S., Bhattacharya, Tanmoy, Haynes, Barton F., Korber, Bette T., Hahn, Beatrice H., Shaw, George M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715054/
https://ncbi.nlm.nih.gov/pubmed/19487424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090378
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