Identification of a Pyridopyrimidinone Inhibitor of Orthopoxviruses from a Diversity-Oriented Synthesis Library

Orthopoxviruses include the prototypical vaccinia virus, the emerging infectious agent monkeypox virus, and the potential biothreat variola virus (the causative agent of smallpox). There is currently no FDA-approved drug for humans infected with orthopoxviruses. We screened a diversity-oriented synt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dower, Ken, Filone, Claire Marie, Hodges, Erin N., Bjornson, Zach B., Rubins, Kathleen H., Brown, Lauren E., Schaus, Scott, Hensley, Lisa E., Connor, John H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Vaccines and Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302283/
https://ncbi.nlm.nih.gov/pubmed/22205744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05416-11
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