Coordinate Deletion of N-Glycans from the Heptad Repeats of the Fusion F Protein of Newcastle Disease Virus Yields a Hyperfusogenic Virus with Increased Replication, Virulence, and Immunogenicity

The role of N-linked glycosylation of the Newcastle disease virus (NDV) fusion (F) protein in viral replication and pathogenesis was examined by eliminating potential acceptor sites using a reverse genetics system for the moderately pathogenic strain Beaudette C (BC). The NDV-BC F protein contains s...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Samal, Sweety, Khattar, Sunil K., Kumar, Sachin, Collins, Peter L., Samal, Siba K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302274/
https://ncbi.nlm.nih.gov/pubmed/22205748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06380-11
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky