The Receptor Binding Specificity of the Live Attenuated Influenza H2 and H6 Vaccine Viruses Contributes to Vaccine Immunogenicity and Protection in Ferrets

To prepare for influenza pandemics that may be caused by the H2 and H6 subtype influenza viruses, live attenuated influenza virus (LAIV) H2 and H6 vaccines are being developed and evaluated. The H2 and H6 vaccine candidates with different receptor binding preferences specified by amino acid substitu...

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Bibliographic Details
Main Authors: Chen, Zhongying, Zhou, Helen, Kim, Lomi, Jin, Hong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302243/
https://ncbi.nlm.nih.gov/pubmed/22190726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06219-11
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