PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells

Transient receptor potential vanilloid channel 4 (TRPV4) is a polymodally activated nonselective cationic channel implicated in the regulation of vasodilation and hypertension. We and others have recently shown that cyclic stretch and shear stress activate TRPV4-mediated calcium influx in endothelia...

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Autori principali: Adapala, Ravi K., Talasila, Phani K., Bratz, Ian N., Zhang, David X., Suzuki, Makoto, Meszaros, J. Gary, Thodeti, Charles K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
Soggetti:
Vascular Biology and Microcirculation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302191/
https://ncbi.nlm.nih.gov/pubmed/21705673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00142.2011
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