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HIV-2 VIRAL PROTEIN X (Vpx) UBIQUITINATION IS DISPENSABLE FOR UBIQUITIN LIGASE INTERACTION AND EFFECTS ON MACROPHAGE INFECTION

HIV-2 Vpx, a virus-associated accessory protein, is critical for infection of non-dividing myeloid cells. To understand the function of Vpx ubiquitination, interaction with an E3 ubiquitin ligase complex, and ability to overcome an inhibition of reverse transcription, we analyzed Vpx lysine mutants...

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Detalhes bibliográficos
Main Authors: McCulley, Anna, Ratner, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302174/
https://ncbi.nlm.nih.gov/pubmed/22386056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.02.002
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