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HIV-2 VIRAL PROTEIN X (Vpx) UBIQUITINATION IS DISPENSABLE FOR UBIQUITIN LIGASE INTERACTION AND EFFECTS ON MACROPHAGE INFECTION
HIV-2 Vpx, a virus-associated accessory protein, is critical for infection of non-dividing myeloid cells. To understand the function of Vpx ubiquitination, interaction with an E3 ubiquitin ligase complex, and ability to overcome an inhibition of reverse transcription, we analyzed Vpx lysine mutants...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302174/ https://ncbi.nlm.nih.gov/pubmed/22386056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.02.002 |
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