Characterization of a new animal model of metabolic syndrome: the DahlS.Z-Lepr(fa)/Lepr(fa) rat

OBJECTIVE: The DahlS.Z-Lepr(fa)/Lepr(fa) (DS/obese) rat strain was established from a cross between Dahl salt-sensitive rats and Zucker fatty (fa/fa) rats, the latter of which harbor a missense mutation in the leptin receptor gene (Lepr). We examined whether DS/obese rats might be a suitable animal...

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Detalhes bibliográficos
Main Authors: Hattori, T, Murase, T, Ohtake, M, Inoue, T, Tsukamoto, H, Takatsu, M, Kato, Y, Hashimoto, K, Murohara, T, Nagata, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302131/
https://ncbi.nlm.nih.gov/pubmed/23154293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2010.1
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