New photoactivatable structural and affinity probes of RNAs: specific features and applications for mapping of spermine binding sites in yeast tRNA(Asp) and interaction of this tRNA with yeast aspartyl-tRNA synthetase.

Aryldiazonium salts are shown to be useful as phototriggered structural probes for RNA mapping as well as for footprinting of RNA/protein interaction. In particular the yeast tRNA(Asp)/aspartyl-tRNA synthetase complex is shown to involve the variable loop face and the concave side of the L-shaped nu...

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Main Authors: Garcia, A, Giegé, R, Behr, J P
Format: Artigo
Jezik:Inglês
Izdano: 1990
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC330207/
https://ncbi.nlm.nih.gov/pubmed/2408010
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