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New photoactivatable structural and affinity probes of RNAs: specific features and applications for mapping of spermine binding sites in yeast tRNA(Asp) and interaction of this tRNA with yeast aspartyl-tRNA synthetase.

Aryldiazonium salts are shown to be useful as phototriggered structural probes for RNA mapping as well as for footprinting of RNA/protein interaction. In particular the yeast tRNA(Asp)/aspartyl-tRNA synthetase complex is shown to involve the variable loop face and the concave side of the L-shaped nu...

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Pubblicato in:Nucleic Acids Res
Autori principali: Garcia, A, Giegé, R, Behr, J P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1990
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330207/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2408010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.1.89
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