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New synthetic routes to protected purine 2'-O-methylriboside-3'-O-phosphoramidites using a novel alkylation procedure.

A highly selective alkylation procedure has been developed enabling new synthetic routes to be established for protected purine 2'-O-methylriboside-3'-O-phosphoramidites; building blocks for the assembly of 2'-O-methyloligoribonucleotides. The new procedure avoids the use of the highly toxic and pot...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Sproat, B S, Beijer, B, Iribarren, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1990
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2308835/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.1.41
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