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Eukaryotic topoisomerase II preferentially cleaves alternating purine-pyrimidine repeats.

Alternating purine-pyrimidine sequences (RY repeats) demonstrate considerable homology to the consensus sequence for vertebrate topoisomerase II (Spitzner and Muller (1988) Nucleic Acids Res. 16: 1533-1556). This is shown below and positions that can match are underscored. RYRYRYRYRYRYRYRYRY = alter...

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Udgivet i:Nucleic Acids Res
Principais autores: Spitzner, J R, Chung, I K, Muller, M T
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1990
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2155393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.1.1
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