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Bim is required for T-cell allogeneic responses and graft-versus-host disease in vivo

Bim, a BH3-only Bcl-2-family protein, is essential for T-cell negative selection in the thymus as well as for the death of activated T cells in the periphery. The role of Bim has been extensively studied in T-cell responses to self-antigens and viral infections. Recent findings on Bim in autoimmunit...

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Autors principals: Yu, Yu, Yu, Jing, Iclozan, Cristina, Kaosaard, Kane, Anasetti, Claudio, Yu, Xue-Zhong
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3301434/
https://ncbi.nlm.nih.gov/pubmed/22432091
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