Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function

Translation of the TnaC nascent peptide inhibits ribosomal activity in the presence of l-tryptophan, inducing expression of the tnaCAB operon in Escherichia coli. Using chemical methylation, this work reveals how interactions between TnaC and the ribosome are affected by mutations in both molecules....

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Detalles Bibliográficos
Main Authors: Martínez, Allyson K., Shirole, Nitin H., Murakami, Shino, Benedik, Michael J., Sachs, Matthew S., Cruz-Vera, Luis R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299997/
https://ncbi.nlm.nih.gov/pubmed/22110039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1052
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