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Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function

Translation of the TnaC nascent peptide inhibits ribosomal activity in the presence of l-tryptophan, inducing expression of the tnaCAB operon in Escherichia coli. Using chemical methylation, this work reveals how interactions between TnaC and the ribosome are affected by mutations in both molecules....

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Détails bibliographiques
Auteurs principaux: Martínez, Allyson K., Shirole, Nitin H., Murakami, Shino, Benedik, Michael J., Sachs, Matthew S., Cruz-Vera, Luis R.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299997/
https://ncbi.nlm.nih.gov/pubmed/22110039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1052
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