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Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function
Translation of the TnaC nascent peptide inhibits ribosomal activity in the presence of l-tryptophan, inducing expression of the tnaCAB operon in Escherichia coli. Using chemical methylation, this work reveals how interactions between TnaC and the ribosome are affected by mutations in both molecules....
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Oxford University Press
2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299997/ https://ncbi.nlm.nih.gov/pubmed/22110039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1052 |
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