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Lovastatin inhibits proliferation of rat mesangial cells.

Products of intracellular mevalonate metabolism are essential for cell growth and proliferation. Lovastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, blocks the formation of mevalonate and its metabolites, and has been shown to inhibit proliferation of several cell types. In...

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Bibliografski detalji
Glavni autori: O'Donnell, M P, Kasiske, B L, Kim, Y, Atluru, D, Keane, W F
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC329998/
https://ncbi.nlm.nih.gov/pubmed/8423236
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