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Thiostrepton is an Inducer of Oxidative and Proteotoxic Stress that Impairs Viability of Human Melanoma Cells but not Primary Melanocytes
Pharmacological induction of oxidative and proteotoxic stress has recently emerged as a promising strategy for chemotherapeutic intervention targeting cancer cells. Guided by a differential phenotypic drug screen for novel lead compounds that selectively induce melanoma cell apoptosis without compro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299892/ https://ncbi.nlm.nih.gov/pubmed/22321511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.01.027 |
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