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Thiostrepton is an Inducer of Oxidative and Proteotoxic Stress that Impairs Viability of Human Melanoma Cells but not Primary Melanocytes

Pharmacological induction of oxidative and proteotoxic stress has recently emerged as a promising strategy for chemotherapeutic intervention targeting cancer cells. Guided by a differential phenotypic drug screen for novel lead compounds that selectively induce melanoma cell apoptosis without compro...

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Bibliografiske detaljer
Main Authors: Qiao, Shuxi, Lamore, Sarah D., Cabello, Christopher M., Lesson, Jessica L., Muñoz-Rodriguez, José L., Wondrak, Georg T.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299892/
https://ncbi.nlm.nih.gov/pubmed/22321511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.01.027
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