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Fluorescence Assay of Polyamide-DNA Interactions

Polyamides (PA) are distamycin-type ligands of DNA that bind the minor groove and are capable of sequence selective recognition. This capability provides a viable route to their development as therapeutics. Presented here is a simple and convenient fluorescence assay for polyamide-DNA binding. PAs a...

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Detalhes bibliográficos
Main Authors: Dupureur, Cynthia M., Bashkin, James K., Aston, Karl, Koeller, Kevin J., Gaston, Kimberly R., He, Gaofei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299850/
https://ncbi.nlm.nih.gov/pubmed/22342620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.01.017
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