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Detection of PIGO-Deficient Cells Using Proaerolysin: A Valuable Tool to Investigate Mechanisms of Mutagenesis in the DT40 Cell System
While isogenic DT40 cell lines deficient in DNA repair pathways are a great tool to understand the DNA damage response to genotoxic agents by a comparison of cell toxicity in mutants and parental DT40 cells, no convenient mutation assay for mutagens currently exists for this reverse-genetic system....
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Autors principals: | , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science
2012
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299801/ https://ncbi.nlm.nih.gov/pubmed/22428069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033563 |
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