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Angiotensin II Requires Zinc and Downregulation of the Zinc Transporters ZnT3 and ZnT10 to Induce Senescence of Vascular Smooth Muscle Cells

Senescence, a hallmark of mammalian aging, is associated with the onset and progression of cardiovascular disease. Angiotensin II (Ang II) signaling and zinc homeostasis dysfunction are increased with age and are linked to cardiovascular disease, but the relationship among these processes has not be...

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Detalhes bibliográficos
Main Authors: Patrushev, Nikolay, Seidel-Rogol, Bonnie, Salazar, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299759/
https://ncbi.nlm.nih.gov/pubmed/22427991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033211
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