Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic β-cell function

Genetic studies suggest that Zn transporters such as ZnT8 play a role in insulin secretion by pancreatic β-cells; however, little is known about the dynamic roles of Zn trafficking pathways on β-cell physiology. To test the acute effects of the inflammatory cytokines interleukin 1β (IL1β) and tumor...

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Detalhes bibliográficos
Main Authors: Muayed, Malek El, Billings, Liana K, Raja, Meera R, Zhang, Xiaomin, Park, Paul J, Newman, Marsha V, Kaufman, Dixon B, O’Halloran, Thomas V, Lowe, William L
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088990/
https://ncbi.nlm.nih.gov/pubmed/20508080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0420
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