Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria.

The bactericidal/permeability-increasing protein (BPI) of neutrophils and BPI fragments neutralize the effects of isolated Gram-negative bacterial lipopolysaccharides both in vitro and in vivo. Since endotoxin most commonly enters the host as constituents of invading Gram-negative bacteria, we raise...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Weiss, J, Elsbach, P, Shu, C, Castillo, J, Grinna, L, Horwitz, A, Theofan, G
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1522221/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115930
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires