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The Homeostatic Chemokine CCL21 Predicts Mortality and May Play a Pathogenic Role in Heart Failure

BACKGROUND: CCL19 and CCL21, acting through CCR7, are termed homeostatic chemokines. Based on their role in concerting immunological responses and their proposed involvement in tissue remodeling, we hypothesized that these chemokines could play a pathogenic role in heart failure (HF). METHODOLOGY/PR...

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Detalhes bibliográficos
Main Authors: Yndestad, Arne, Finsen, Alexandra Vanessa, Ueland, Thor, Husberg, Cathrine, Dahl, Christen P., Øie, Erik, Vinge, Leif Erik, Sjaastad, Ivar, Sandanger, Øystein, Ranheim, Trine, Dickstein, Kenneth, Kjekshus, John, Damås, Jan Kristian, Fiane, Arnt E., Hilfiker-Kleiner, Denise, Lipp, Martin, Gullestad, Lars, Christensen, Geir, Aukrust, Pål
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299722/
https://ncbi.nlm.nih.gov/pubmed/22427939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033038
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