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Estimating the mode of inheritance in genetic association studies of qualitative traits based on the degree of dominance index
BACKGROUND: The biological justification for the choice of the genetic mode in genetic association studies (GAS) is seldom available. Then, the mode of inheritance is approximated by investigating a number of non-orthogonal genetic contrasts making the interpretation of results difficult. METHODS: W...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299619/ https://ncbi.nlm.nih.gov/pubmed/22188898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-11-171 |
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