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Analysis of complex human genetic traits: an ordered-notation method and new tests for mode of inheritance.

A novel ordered notation is introduced that allows description and calculation of the probability of any nuclear-pedigree configuration of disease status and marker-allele information. Algorithms are given that allow for complex models of disease predisposition, a highly polymorphic or less polymorp...

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Detalhes bibliográficos
Autor principal: Thomson, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801559/
https://ncbi.nlm.nih.gov/pubmed/7668274
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