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Analysis of complex human genetic traits: an ordered-notation method and new tests for mode of inheritance.

A novel ordered notation is introduced that allows description and calculation of the probability of any nuclear-pedigree configuration of disease status and marker-allele information. Algorithms are given that allow for complex models of disease predisposition, a highly polymorphic or less polymorp...

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Autore principale: Thomson, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801559/
https://ncbi.nlm.nih.gov/pubmed/7668274
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