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Analysis of complex human genetic traits: an ordered-notation method and new tests for mode of inheritance.
A novel ordered notation is introduced that allows description and calculation of the probability of any nuclear-pedigree configuration of disease status and marker-allele information. Algorithms are given that allow for complex models of disease predisposition, a highly polymorphic or less polymorp...
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Natura: | Artigo |
Lingua: | Inglês |
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1995
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1801559/ https://ncbi.nlm.nih.gov/pubmed/7668274 |
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