SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9

Upregulation of the matrix metalloproteinase MMP-9 plays a central role in tumor progression and metastasis by stimulating cell migration, tumor invasion and angiogenesis. To gain insights into MMP-9 expression, we investigated its epigenetic control in a reversible model of cancer that is initiated...

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Главные авторы: Cock-Rada, Alicia M., Medjkane, Souhila, Janski, Natacha, Yousfi, Nadhir, Perichon, Martine, Chaussepied, Marie, Chluba, Johanna, Langsley, Gordon, Weitzman, Jonathan B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299564/
https://ncbi.nlm.nih.gov/pubmed/22194464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1052
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