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Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in HdeB and May Have a Role in Periplasmic Chaperone Function

Escherichia coli and Gram-negative bacteria that live in the human gut must be able to tolerate rapid and large changes in environmental pH. Low pH irreversibly denatures and precipitates many bacterial proteins. While cytoplasmic proteins are well buffered against such swings, periplasmic proteins...

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Detalhes bibliográficos
Main Authors: Wang, Wenjian, Rasmussen, Tim, Harding, Amanda J., Booth, Nuala A., Booth, Ian R., Naismith, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299563/
https://ncbi.nlm.nih.gov/pubmed/22138344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.11.026
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