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Microemulsion-Based Gel of Terbinafine for the Treatment of Onychomycosis: Optimization of Formulation Using D-Optimal Design

The aim of the present investigation was to evaluate microemulsion as a vehicle for dermal drug delivery and to develop microemulsion-based gel of terbinafine for the treatment of onychomycosis. D-optimal mixture experimental design was adopted to optimize the amount of oil (X(1)), Smix (mixture of...

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Detalhes bibliográficos
Main Authors: Barot, Bhavesh S., Parejiya, Punit B., Patel, Hetal K., Gohel, Mukesh C., Shelat, Pragna K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299475/
https://ncbi.nlm.nih.gov/pubmed/22187363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9742-7
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