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Optimization of a Dual Mechanism Gastrofloatable and Gastroadhesive Delivery System for Narrow Absorption Window Drugs

In order to overcome poor bioavailability of narrow absorption window drugs, a gastrosphere system comprising two mechanisms of gastric retention, namely buoyancy and gastroadhesion, has been investigated in this study employing poly(lactic-co-glycolic acid) (PLGA), polyacrylic acid (PAA), alginate,...

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Bibliografiske detaljer
Main Authors: Murphy, Caragh, Pillay, Viness, Choonara, Yahya E., du Toit, Lisa C., Ndesendo, Valence M. K., Chirwa, Nthato, Kumar, Pradeep
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299464/
https://ncbi.nlm.nih.gov/pubmed/22048877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9711-1
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