Impaired Caveolae Function and Upregulation of Alternative Endocytic Pathways Induced by Experimental Modulation of Intersectin-1s Expression in Mouse Lung Endothelium

Intersectin-1s (ITSN-1s), a protein containing five SH3 (A-E) domains, regulates via the SH3A the function of dynamin-2 (dyn2) at the endocytic site. ITSN-1s expression was modulated in mouse lung endothelium by liposome delivery of either a plasmid cDNA encoding myc-SH3A or a specific siRNA targeti...

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Bibliographic Details
Main Authors: Predescu, Dan N., Neamu, Radu, Bardita, Cristina, Wang, Minhua, Predescu, Sanda A.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299393/
https://ncbi.nlm.nih.gov/pubmed/22506115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/672705
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