Diminished Clostridium difficile toxin A sensitivity in newborn rabbit ileum is associated with decreased toxin A receptor.

Human infants are relatively resistant to Clostridium difficile-associated diarrhea and colitis compared to adults. In that toxin A is the major cause of intestinal damage with this organism, we compared toxin A receptor binding and biological effects in newborn vs adult rabbit ileum. Purified toxin...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Eglow, R, Pothoulakis, C, Itzkowitz, S, Israel, E J, O'Keane, C J, Gong, D, Gao, N, Xu, Y L, Walker, W A, LaMont, J T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115957
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