An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines.

The human myeloid cell line HL60 secretes urokinase-type plasminogen activator (uPA) and expresses its receptor. When stimulated with phorbol myristate acetate (PMA), both secretion of uPA and the expression of its receptor are up-regulated, and these cells differentiate to an adherent phenotype. Th...

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Bibliographic Details
Main Authors: Nusrat, A R, Chapman, H A
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC329905/
https://ncbi.nlm.nih.gov/pubmed/1847936
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