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An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines.
The human myeloid cell line HL60 secretes urokinase-type plasminogen activator (uPA) and expresses its receptor. When stimulated with phorbol myristate acetate (PMA), both secretion of uPA and the expression of its receptor are up-regulated, and these cells differentiate to an adherent phenotype. Th...
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| Udgivet i: | J Clin Invest |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847936/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115070 |
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