Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis.

Despite its affinity for fibrin, tissue plasminogen activator (t-PA) administration causes systemic fibrinogenolysis. To investigate the mechanism, t-PA was incubated with plasma in the presence or absence of a fibrin clot, and the extent of fibrinogenolysis was determined by measuring B beta 1-42....

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Weitz, J I, Leslie, B, Ginsberg, J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1900308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115069
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