Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis.
Despite its affinity for fibrin, tissue plasminogen activator (t-PA) administration causes systemic fibrinogenolysis. To investigate the mechanism, t-PA was incubated with plasma in the presence or absence of a fibrin clot, and the extent of fibrinogenolysis was determined by measuring B beta 1-42....
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1900308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115069 |
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