CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke

BACKGROUND: A brief exposure to systemic hypoxia (i.e., hypoxic preconditioning; HPC) prior to transient middle cerebral artery occlusion (tMCAo) reduces infarct volume, blood-brain barrier disruption, and leukocyte migration. CCL2 (MCP-1), typically regarded as a leukocyte-derived pro-inflammatory...

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Autors principals: Stowe, Ann M, Wacker, Bradley K, Cravens, Petra D, Perfater, Jennifer L, Li, Min K, Hu, Ruilong, Freie, Angela B, Stüve, Olaf, Gidday, Jeffrey M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298779/
https://ncbi.nlm.nih.gov/pubmed/22340958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-33
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