Effect of Renin-Angiotensin-Aldosterone System Inhibition, Dietary Sodium Restriction, and/or Diuretics on Urinary Kidney Injury Molecule 1 Excretion in Nondiabetic Proteinuric Kidney Disease: A Post Hoc Analysis of a Randomized Controlled Trial

BACKGROUND: Tubulointerstitial damage plays an important role in chronic kidney disease (CKD) with proteinuria. Urinary kidney injury molecule 1 (KIM-1) reflects tubular KIM-1 and is considered a sensitive biomarker for early tubular damage. We hypothesized that a decrease in proteinuria by using th...

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Bibliographic Details
Main Authors: Waanders, Femke, Vaidya, Vishal S., van Goor, Harry, Leuvenink, Henri, Damman, Kevin, Hamming, Inge, Bonventre, Joseph V., Vogt, Liffert, Navis, Gerjan
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298772/
https://ncbi.nlm.nih.gov/pubmed/18823687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.ajkd.2008.07.021
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