GDNF protects enteric glia from apoptosis: evidence for an autocrine loop

BACKGROUND: Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We investigated the role of Glial-derived neuro...

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Bibliografiske detaljer
Main Authors: Steinkamp, Martin, Gundel, Heike, Schulte, Nadine, Spaniol, Ulrike, Pflueger, Carolin, Zizer, Eugen, von Boyen, Georg BT
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298702/
https://ncbi.nlm.nih.gov/pubmed/22251670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-6
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