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GDNF protects enteric glia from apoptosis: evidence for an autocrine loop

BACKGROUND: Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We investigated the role of Glial-derived neuro...

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Detalhes bibliográficos
Main Authors: Steinkamp, Martin, Gundel, Heike, Schulte, Nadine, Spaniol, Ulrike, Pflueger, Carolin, Zizer, Eugen, von Boyen, Georg BT
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298702/
https://ncbi.nlm.nih.gov/pubmed/22251670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-6
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